Research Article
Zinc Regulates Glucose Metabolism of the Spinal Cord and Neurons and Promotes Functional Recovery after Spinal Cord Injury through the AMPK Signaling Pathway
Figure 6
Zinc regulated glucose metabolism in the spinal cord of SCI mice through the AMPK pathway. (a–e) The expression levels of PGC-1α, NRF2, NQO1, and HO-1 proteins were assessed by WB at 3 days after injury (). (f, g) Transmission electron microscopy was used to monitor mitochondrial injury in the spinal cord (, and 500 nm). (h–n) Western blots of p-AMPK, AMPK, PGC-1α, GLUT4, NRF2, NQO1, and HO-1 expression after compound C treatment at 3 days after injury (). Data are represented as the . , , and .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |
(i) |
(j) |
(k) |
(l) |
(m) |
(n) |