Ameliorative Effects and Mechanism of Buyang Huanwu Decoction on Pulmonary Vascular Remodeling: Network and Experimental Analyses

Table 1

Top 10 targets directly associated with PH phenotype.

Gene symbol	Description	Score
NOS3	Nitric oxide synthase 3	21.08
ALOX5	Arachidonate 5-lipoxygenase	14.37
SELP	Selectin P	14.25
NPR3	Natriuretic peptide receptor 3	13.96
BMP2	Bone morphogenetic protein 2	13.68
ALB	Albumin	13.56
NOX4	NADPH oxidase 4	13.42
TGFBR1	Transforming growth factor beta receptor 1	13.32
F2	Coagulation factor II, thrombin	12.99
KDR	Kinase insert domain receptor	12.33