The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome

Figure 4

ORY suppressed endoplasmic reticulum stress during HIRI. (a, b) Immunohistochemistry analysis of GRP78 (original magnification ×200). (c, d) Proteins of hepatic tissues were determined by western blotting for the determination of GRP78, p-PERK, p-EIF2S1, and CHOP and β-actin expression. Relative protein abundance was semiquantified by densitometry (). Data were expressed as (SD) values. , , and versus the sham group; ^#, ^##, and ^### versus the I/R group; NS: no significance.

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