Research Article
The Dietary Supplement γ-Oryzanol Attenuates Hepatic Ischemia Reperfusion Injury via Inhibiting Endoplasmic Reticulum Stress and HMGB1/NLRP3 Inflammasome
Figure 8
ORY suppressed AML12 cells from CoCl2- or tunicamycin-induced endoplasmic reticulum stress. (a, b) Western blotting analysis of GRP78, PERK, p-PERK, EIF2S1, p-EIF2S1, CHOP, and β-actin expressions in cells from the control, ORY, CoCl2, and CoCl2+ORY groups. (c, d) Western blotting analysis of GRP78, p-PERK, p-EIF2S1, CHOP, and β-actin expressions in cells from the control, ORY, tunicamycin, and tunicamycin+ORY groups. Relative protein abundance was semiquantified by densitometry (). Data were expressed as (SD) values. , , and versus the control group; #, ##, and ### versus the CoCl2 group.
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