Association of Serum Total Bilirubin Concentration with Telomere Length: The National Health and Nutrition Examination Survey

Table 3

The association between total bilirubin concentrations and mean telomere length by sex.

Total bilirubin, mg/dL	Male ()		Female ()		Total ()
	β (95% CI)	value	β (95% CI)	value	β (95% CI)	value
Crude model
Q1	Ref		Ref		Ref
Q2	0.01 (-0.01, 0.03)	0.567	0.02 (-0.00, 0.04)	0.118	0.02 (-0.00, 0.04)	0.131
Q3	0.03 (0.01, 0.05)	0.112	0.05 (0.03, 0.07)	<0.001	0.04 (0.02, 0.06)	<0.001
Q4	0.04 (0.01, 0.07)	0.017	0.03 (0.00, 0.05)	0.022	0.04 (0.02, 0.05)	<0.001
Q5	0.06 (0.02, 0.09)	<0.001	0.03 (0.00, 0.06)	0.048	0.05 (0.03, 0.07)	<0.001
for trend	<0.001		0.002		<0.001
Adjusted model
Q1	Ref		Ref		Ref
Q2	0.01 (-0.02, 0.05)	0.457	0.03 (0.01, 0.05)	0.015	0.03 (0.01, 0.04)	0.008
Q3	0.03 (-0.01, 0.06)	0.122	0.06 (0.04, 0.08)	<0.001	0.05 (0.03, 0.07)	<0.001
Q4	0.03 (0.00, 0.06)	0.042	0.05 (0.03, 0.07)	<0.001	0.05 (0.03, 0.06)	<0.001
Q5	0.04 (0.00, 0.07)	0.024	0.04 (0.02, 0.07)	0.002	0.05 (0.03, 0.07)	<0.001
for trend	0.013		<0.001		<0.001

Adjusted model adjust for age (continuous), race (non-Hispanic white, black, Mexican American, other Hispanic, other race/ethnicity or missing), education (less than high school, high school, more than high school, or missing), body mass index (<18.5, 18.5- <25, 25- <30, ≥30, or missing), smoke status (none, past, current, or missing), alcohol (yes, no, or missing), physical activity (no aerobic activity, low activity, moderate activity, high activity, or missing), energy intake (Q1-Q4), diabetes (yes, no, or missing), hypertension (yes, no, or missing), and C-reactive protein (Q1-Q3).