Research Article
Downregulation of CYP39A1 Serves as a Novel Biomarker in Hepatocellular Carcinoma with Worse Clinical Outcome
Table 2
Difference of serum biochemical indices between CYP39A1 low expression and CYP39A1 high expression in HCC patients.
| | Serum biochemical indices | CYP39A1 low expression | CYP39A1 high expression | valuea | | |
| | Alanine aminotransferase (ALT) | | | 0.38 | | Aspartic transaminase (AST) | | | 0.93 | | ALT/AST (ratio) | | | 0.01 | | Alkaline phosphatase (ALP) | | | 0.33 | | γ-Glutamyltransferase (GGT) | | | 0.23 | | Total bile acid (TBA) | | | 0.02 | | Prealbumin (PA) | | | <0.001 | | Total protein (TP) | | | 0.42 | | Albumin (ALB) | | | 0.09 | | Globulin (GLB) | | | 0.45 | | Ratio of albumin to globulin (A/G) | | | 0.01 | | Total bilirubin (TBIL) | | | 0.01 | | Direct bilirubin (DBIL) | | | 0.02 | | Leucine aminopeptidase (LAP) | | | 0.25 | | Glutamate dehydrogenase (GLDH) | | | 0.44 | | Fibronectin (Fn) | | | 0.04 | | Urea (urea) | | | 0.28 | | Creatinine (Cr) | | | 0.01 | | Urea nitrogen/creatinine (U/Cr) | | | 0.06 | | β2-microglobulin (β2-m) | | | 0.06 | | Total carbon dioxide (TCO2) | | | 0.19 | | Uric acid (UA) | | | 0.01 | | Total cholesterol (TCh) | | | 0.10 | | Triacylglycerol (TG) | | | 0.62 | | High-density lipoprotein cholesterol (HDL-Ch) | | | 0.79 | | Low-density lipoprotein cholesterin (LDL-Ch) | | | 0.16 | | Total/high density lipoprotein cholesterol (T/HDL-Ch) | | | 0.61 | | Lipoprotein alpha (LP(α)) | | | 0.78 |
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