Fibroblast Growth Factor 13 Facilitates Peripheral Nerve Regeneration through Maintaining Microtubule Stability

Figure 2

Histological analyses of the regenerated sciatic nerves in each group at 6 weeks after transection injury. (a) Representative costaining images for NF-200 and MBP of longitudinal sections in each experimental group. The scale bars in lower and higher magnifications were 500 μm and 20 μm, respectively. (b) Schema of nerve regeneration counting method proximal to the original transection through fields of the corresponding regenerating cable. (c) Quantification of total axon numbers in different fields of the indicated groups. (d, e) Quantitative analyses of average fluorescence intensity for NF-200 and MBP in indicated region of whole regenerated cable. Data are shown as , . PNI vs. control: , , and ; FGF13 vs. vehicle: ^& and ^&&; FGF13 vs. PNI: ^# and ^##.

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