Fibroblast Growth Factor 13 Facilitates Peripheral Nerve Regeneration through Maintaining Microtubule Stability

Figure 7

FGF13 induces microtubule stabilization in SCs. (a) Representative images of immunoblotting analysis of acetylated tubulin, tyrosinated tubulin, Tau, Kinesin-5, and Dynein in the control, myelin, and myelin+FGF13 groups. (b–e) Quantification results of the levels of the indicated proteins from (a). GAPDH was used as the loading control and for band density normalization. (f, g) Representative confocal images of Ace-tubulin and Tyr-tubulin fluorescence and quantitative results of A/T ratio in the different experimental groups. DAPI was used to label the nuclei. All these data represent the and sourced from three independent experiments. and vs. the control group; ^## and ^### vs. the myelin group.

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