ALKBH5 Exacerbates Aortic Dissection by Promoting Inflammatory Response and Apoptosis of Aortic Smooth Muscle Cells via Regulating lnc-TMPO-AS1/EZH2/IRAK4 Signals in an m6A Modification Manner

<div>Schematic diagram of the mechanisms revealed in this study. ALKBH5 could aggravate AngII-induced inflammation response as well as apoptosis of HASMCs and increase the incidence of AD in AngII-infused mice through regulating lnc-TMPO-AS1/EZH2/IRAK4 signals in an m6A modification manner.</div>

Oxidative Medicine and Cellular Longevity

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Figure 7

Figure 7: ALKBH5 Exacerbates Aortic Dissection by Promoting Inflammatory Response and Apoptosis of Aortic Smooth Muscle Cells via Regulating lnc-TMPO-AS1/EZH2/IRAK4 Signals in an m6A Modification Manner 

Figure 7 | ALKBH5 Exacerbates Aortic Dissection by Promoting Inflammatory Response and Apoptosis of Aortic Smooth Muscle Cells via Regulating lnc-TMPO-AS1/EZH2/IRAK4 Signals in an m6A Modification Manner 