Rosiglitazone Suppresses Renal Crystal Deposition by Ameliorating Tubular Injury Resulted from Oxidative Stress and Inflammatory Response via Promoting the Nrf2/HO-1 Pathway and Shifting Macrophage Polarization

<div>Genetic expression of macrophage-related molecules, proinflammatory cytokines, and anti-inflammatory cytokines. (a) mRNA levels in THP-1 cells stimulated with COM or ROSI (1 <i>μ</i>M) or GW9662 (10 <i>μ</i>M) by qRT-PCR. (b) Genetic expression determined by Western blot. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Rosiglitazone Suppresses Renal Crystal Deposition by Ameliorating Tubular Injury Resulted from Oxidative Stress and Inflammatory Response via Promoting the Nrf2/HO-1 Pathway and Shifting Macrophage Polarization 

Figure 7 | Rosiglitazone Suppresses Renal Crystal Deposition by Ameliorating Tubular Injury Resulted from Oxidative Stress and Inflammatory Response via Promoting the Nrf2/HO-1 Pathway and Shifting Macrophage Polarization 