Research Article
Mitochondrial Dysfunction Contributes to Aging-Related Atrial Fibrillation
Table 1
Clinical and biochemical characteristics of AF patients and controls.
| | Characteristic | The controls () | AF patients () | value |
| | Clinical parameters | | Age (years) | | | 0.629 | | Male, (%) | 96 (100) | 96 (100) | 1.000 | | BMI (kg/m2) | | | 0.106 | | Smoking, (%) | 16 (16.67) | 21 (21.88) | 0.363 | | History of CHD, (%) | 21 (21.88) | 18 (18.75) | 0.593 | | Hypertension, (%) | 42 (43.75) | 47 (48.96) | 0.472 | | Diabetes mellitus, (%) | 15 (15.62) | 17 (17.71) | 0.700 | | Hyperlipidemia | 24 (25.00) | 20 (20.83) | 0.495 | | Antihypertensive medication, (%) | 42 (43.75) | 46 (47.92) | 0.565 | | Glucose lowering treatment, (%) | 14 (14.58) | 15 (15.63) | 0.841 | | Lipid-lowering medication, (%) | 41 (42.71) | 34 (35.42) | 0.303 | | SBP (mmHg) | | | 0.382 | | DBP (mmHg) | | | 0.109 | | Laboratory parameters | | TC (mmol/L) | | | 0.464 | | TG (mmol/L) | | | 0.107 | | LDL-C (mmol/L) | | | 0.236 | | HDL-C (mmol/L) | | | 0.283 | | Cr (mmol/L) | | | 0.077 | | BUN (mmol/L) | | | 0.299 | | UA (mmol/L) | | | 0.025 | | FBG (mmol/L) | | | 0.829 | | GHb (%) | | | 0.311 | | CRP (mg/dL) | | | 0.077 | | Echocardiographic parameters | | LVEF (%) | | | 0.056 | | LAD (mm) | | | 0.028 |
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Abbreviations: BMI: body mass index; CHD: coronary heart disease; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; Cr: creatinine; BUN: blood urea nitrogen; UA: uric acid; FBG: fasting blood glucose; GHb: glycated hemoglobin; CRP: C-reactive protein; LVEF: left ventricular ejection fraction; LAD: left atrial diameter. with italic font means statistically significant. |