Polycyclic Aromatic Hydrocarbons from Fine Particulate Matter Induce Oxidative Stress and the Inflammatory Response in Human Vocal Fold Fibroblast Cells

<div>AhR and CYP1A1 knockdown inhibited PM-induced ROS generation in hVFFs transfected with either AhR or CYP1A1 siRNA before treatment for 24 h with PM (25 <i>μ</i>g/mL). (a) Intracellular ROS levels were determined using the DCFH-DA probe by inverted fluorescence microscopy (magnification, 200x). Green color indicates DCF-positive cells. (b) Relative intensity of DCF fluorescence. All experiments were performed in triplicate. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Polycyclic Aromatic Hydrocarbons from Fine Particulate Matter Induce Oxidative Stress and the Inflammatory Response in Human Vocal Fold Fibroblast Cells 

Figure 5 | Polycyclic Aromatic Hydrocarbons from Fine Particulate Matter Induce Oxidative Stress and the Inflammatory Response in Human Vocal Fold Fibroblast Cells 