Adiponectin Treatment Attenuates Cerebral Ischemia-Reperfusion Injury through HIF-1α-Mediated Antioxidation in Mice

Figure 9

ADPN promoted angiogenesis and improved long-term neurobehavioral outcome. (a) Representative photomicrographs of atrophy volume. (b) The atrophy volume as percentages of the contralateral hemisphere is presented as the and analyzed by one-way ANOVA with Tukey’s posttest. (c) The scoring system of Garcia et al. was evaluated on day 28 after reperfusion. The data are presented as the median with interquartile range and analyzed by the Kruskal-Wallis test followed by Dunn’s test. (d) The total steps on day 28 after reperfusion. (e) The error ratio on day 28 after reperfusion. (f) Representative photomicrographs of angiogenesis. (g) Microvessel density statistics. (h) Western blotting analysis of vWF protein expression. These data except for the Garcia et al. score are presented as the and analyzed by one-way ANOVA with Tukey’s posttest. compared to the vehicle group. per group.

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