Dietary Beta-Hydroxy Beta-Methyl Butyrate Supplementation Alleviates Liver Injury in Lipopolysaccharide-Challenged Piglets

Figure 6

The mRNA expression of toll-like receptor 4 (TLR4) and nucleotide-binding oligomerization domain protein (NODs) and their downstream signaling molecules in the liver of piglets injected with LPS or saline. Values are means, with their standard errors represented by vertical bars (). ^a,bMean values with different letters were considered to be significantly different (). CON: control; HMB: β-hydroxy-β-methylbutyrate; IRAK1: IL-1 receptor-associated kinase 1; LPS: lipopolysaccharide; MyD88: myeloid differentiation factor 88; RIPK2: receptor-interacting serine/threonine-protein kinase 2; TRAF6: TNF-α receptor-associated factor 6.