Bioactive Compounds of Raspberry Oil Emulsions Induced Oxidative Stress via Stimulating the Accumulation of Reactive Oxygen Species and NO in Cancer Cells

Figure 3

In vitro antiproliferative activity of oil emulsion from raspberry oils extracted by supercritical CO₂ (ROSCO2) and cold pressed (ROCOP) against human cancer and normal cell lines. Antiproliferative effect of oil emulsions in 0.5%, 1%, 2%, 5%, and 10% concentrations on colon adenocarcinoma cell line (LoVo), doxorubicin-resistant colon adenocarcinoma cell line (LoVo/DX), breast cancer cell line (MCF7), doxorubicin-resistant breast cancer cell line (MCF7/DX), lung cancer cell line (A549), and normal human dermal fibroblast (NHDF). Cell growth percentage was analyzed with sulforhodamine B (SRB) assay. The results were compared to control and expressed as . —cells with tested oils; —a negative control culture (cells without tested oils). Linear regression model and coefficients of determination were calculated.

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