SM22<i>α</i> Loss Contributes to Apoptosis of Vascular Smooth Muscle Cells via Macrophage-Derived circRasGEF1B

<div>Macrophage infiltration and VSMC apoptosis increase in the aortic media of <i>Sm22α</i><sup>-/-</sup> mice with Ang II infusion. All mice were infused with saline (Ang II-) or Ang II (Ang II+) for 4 weeks. (a, b) Representative immunostaining of CD68 and CD14 in the abdominal aortas from WT or <i>Sm22α<sup>-/-</sup></i> mice. Bars: 50 <i>μ</i>m (a) or 100 <i>μ</i>m (b). (c) Representative immunohistochemical staining of TUNEL and SM <i>α</i>-actin in abdominal aortas of WT and <i>Sm22α<sup>-/-</sup></i> mice. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: SM22<i>α</i> Loss Contributes to Apoptosis of Vascular Smooth Muscle Cells via Macrophage-Derived circRasGEF1B 

Oxidative Medicine and Cellular Longevity

SM22α Loss Contributes to Apoptosis of Vascular Smooth Muscle Cells via Macrophage-Derived circRasGEF1B

Figure 1