Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1<i>α</i> Signaling Pathway

<div>JTXK granules improved glucose tolerance, insulin sensitivity, and lipid profiles in diabetic mice. (a) OGTT test results and (b) area under the curve. (c) Fasting blood glucose. (d) ITT test and (e) area under the curve. (f) Fasting serum insulin level. (g) Homeostasis model assessment: insulin resistance in each group after treatment. Lipid profiles are represented by serum (h) free fatty acid, (i) total cholesterol, (j) triglyceride, (k) LDL-C, and (l) HDL-C contents. NC, DM, Met, and JTXK mean the normal control, diabetes, metformin, and Jiang Tang Xiao Ke granule groups, respectively. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1<i>α</i> Signaling Pathway 

Oxidative Medicine and Cellular Longevity

Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway

Figure 2