Protective Effect of Jiang Tang Xiao Ke Granules against Skeletal Muscle IR via Activation of the AMPK/SIRT1/PGC-1α Signaling Pathway

Figure 6

Effect of JTXK granule drug-containing serum on AMPK/SIRT1/PGC-1α signaling in IR C2C12 cells. (a–g) Protein expressions of AMPKα, SIRT1, PGC-1α, PPARα, UCP3, and CPT1 measured by western blotting. (h–m) Relative gene expressions of AMPKα, SIRT1, PGC-1α, PPARα, UCP3, and CPT1 measured by RT-PCR. Con, Met, and DCS mean the control, metformin, and drug-containing serum of Jiang Tang Xiao Ke granules, respectively. Data were presented as . , compared with the Con group.

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