Artemisinin Reverses Glucocorticoid-Induced Injury in Bone Marrow-Derived Mesenchymal Stem Cells through Regulation of ERK1/2-CREB Signaling Pathway

Figure 8

DEXA inhibited the ERK1/2-CREB signaling pathway. (a) BMSCs were seeded into a 6-well plate at a density of 1- cells/mL and treated with different concentrations of DEXA (0-300 μM) for 24 h. The expression levels of P-ERK1/2, P-CREB, P-AKT, BCL-2, and Bax were assessed by Western blot analysis (). (b–d) Quantification of (a). , , and were considered significantly different in comparison to the control group (0 μM).

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