Kirenol Inhibits B[a]P-Induced Oxidative Stress and Apoptosis in Endothelial Cells via Modulation of the Nrf2 Signaling Pathway

Figure 8

KRL suppresses DNA damage and apoptosis induced by B[a]P in HUVECs cells. (a) The pretreatment of cells was done using B[a]P (5 μmol) or KRL (5, 10, and 25 μmol) for a period of 24 hours and studied the TUNEL assay. (b) Cells were exposed to KRL and/or B[a]P for 24 h, and western blot was executed. Data was represented as the of triplicate values (), and represents noteworthy differences in comparison to control. ^# represents major variations in comparison to B[a]P alone and KRL with the B[a]P treatment groups.

(a)

(b)