Stimulation of AMPK Prevents Diabetes-Induced Photoreceptor Cell Degeneration

Figure 2

AMPK stimulation inhibited AGE-induced 661w cell apoptosis. (a) The viability of 661w cells was measured by CCK-8 assays after AGE and metformin treatment. The effect of AMPK stimulation on the expression of p-AMPK (b, c), Bcl-2 (b, f), and Bax (b, g) after AGE treatment. (d, e) The effect of AMPK stimulation on AGE-induced 661w cell apoptosis was examined by flow cytometry. The data are expressed as the ( for each group). , , .

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