GPA Peptide Attenuates Sepsis-Induced Acute Lung Injury in Mice via Inhibiting Oxidative Stress and Pyroptosis of Alveolar Macrophage

Figure 1

GPA peptide protected mice from CLP-induced ALI in animal models. Effects of GPA peptide on pulmonary inflammation and survival of CLP-induced septic mice. (a–f) After 72 h interventions, illustrative images of H&E staining of lung tissues from each cohort (/cohort). The . (g) Lung injury score. (h) Lung edema. (i) Mice were intravenously administered with GPA peptide (150 mg/kg) in sham+GPA and CLP+GPA cohorts, and mice’s survival rates were followed up for eight days. Data are shown as . , vs. the sham cohort; ^#, ^##, and ^### vs. the CLP cohort.

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