Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H<sub>2</sub>O<sub>2</sub>-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways

<div>Effects of CPM on PI3K/Akt-Nrf2/HO-1 signaling pathway in H<sub>2</sub>O<sub>2</sub>-induced PC12 cells. (a) Effects of CPM on Bcl-2 and caspase family proteins; (b) effects of CPM on PI3K/Akt signaling; (c) effects of CPM on Nrf2/HO-1 signaling. PC12 cells were treated with CPM (60, 80, and 100 <i>μ</i>g/mL) for 2 h, subsequently subjected to H<sub>2</sub>O<sub>2</sub> (200 <i>μ</i>M) for 4 h. All these protein expressions were determined by western blotting assays. 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Oxidative Medicine and Cellular Longevity

fig10

Figure 10

Figure 10: Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H<sub>2</sub>O<sub>2</sub>-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways 

Figure 10 | Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H2O2-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways 