Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H₂O₂-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways

Figure 4

Histological analysis and Nissl staining analysis of hippocampal CA1 and CA3 areas (100x and 400x): (a) H&E staining; (b) Nissl staining; (c) statistical charts for injury index and number of black neurons. Mice were divided into five groups: normal group (normal mice were treated with normal saline alone, 20 mL/kg, p.o.), model group (mice were treated with PTZ and normal saline), and three tested CPM groups (mice were treated with PTZ and CPM at the doses of 100, 200, and 400 mg/kg, p.o.). Data were expressed as (), and vs. model.

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