Antiepileptic Effects of Cicadae Periostracum on Mice and Its Antiapoptotic Effects in H₂O₂-Stimulated PC12 Cells via Regulation of PI3K/Akt/Nrf2 Signaling Pathways

Figure 9

Effects of CPM on ROS levels (a) and antioxidant enzyme activities (b) in H₂O₂-induced PC12 cells. PC12 cells were treated with CPM (60, 80, and 100 μg/mL) for 2 h, subsequently subjected to H₂O₂ (200 μM) for 4 h. The intracellular ROS levels were observed by laser confocal microscopy. The levels of MDA and activities of SOD, CAT, and GSH-Px were determined by commercial assay kits. Data were expressed as (), and vs. model.

(a)

(b)