Imbalance of Autophagy and Apoptosis Induced by Oxidative Stress May Be Involved in Thyroid Damage Caused by Sleep Deprivation in Rats

Figure 3

Sleep deprivation induced thyroid function changes in rats. Serum levels of (a) TT4, (b) TT3, (c) FT4, (d) FT3, and (e) TSH were determined. TT3 increased in the SD group compared with the CC and TC groups ( in each group). (g) Western blotting showed that (i) TPO protein expression in the thyroid was higher but (h) Tg protein expression was lower in the SD group compared with the CC group and TC groups ( in each group). Data are shown as the mean (bar) and standard deviation (whisker) or median(bar) with scatter plots showed. , , compared with rats in the CC or TC group. In TSH comparison, an outlier in the SD group was eliminated.

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