Microglia Polarization from M1 toward M2 Phenotype Is Promoted by Astragalus Polysaccharides Mediated through Inhibition of miR-155 in Experimental Autoimmune Encephalomyelitis

Figure 6

miR-155-mediated APS regulated the phenotypic polarization of microglia. The transfection efficiency was observed by fluorescence imaging (a, b). The expression level of miR-155 was detected by qRT-PCR (c). The relative mRNA expression levels of M1 polarization markers (iNOS) and M2 polarization markers (Arg-1) were detected under the induction of miR-155 mimic (d, e) and inhibitor (f, g) by QRT-PCR. The relative mRNA expression levels of iNOS and Arg-1 after APS intervention induced by miR-155 inhibitor (h, i) by QRT-PCR. , .

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