Early Perihematomal Edema Expansion: Definition, Significance, and Association with Outcomes after Intracerebral Hemorrhage

Table 3

Univariate and multivariate analysis of predictors for early PHE expansion.

Variable	Odds ratio	95% confidence interval	value
Univariate analysis
Age, year^a	1.00	0.97-1.02	0.839
Sex, male	1.60	0.83-3.07	0.160
Alcohol consumption	1.49	0.82-2.73	0.195
Smoking	1.73	0.94-3.16	0.077
Hypertension	1.02	0.51-1.96	0.949
Diabetes mellitus	1.19	0.47-2.99	0.715
Systolic blood pressure, mmHg^a	1.02	1.01-1.03	0.005
Admission GCS score^a	0.86	0.78-0.93	<0.001
Baseline ICH volume, mL^a	1.10	1.06-1.13	<0.001
IVH at baseline CT	0.89	0.47-1.71	0.736
Time from onset to CT, hour^a	0.66	0.52-0.83	<0.001
Multivariate analysis
Systolic blood pressure, mmHg^a	1.02	1.00-1.03	0.022
Admission GCS score^a	0.95	0.85-1.06	0.388
Baseline ICH volume, mL^a	1.11	1.07-1.15	<0.001
Time from onset to CT, hour^a	0.59	0.44-0.78	<0.001

ICH: intracerebral hemorrhage; CT: computed tomography; IVH: intraventricular hemorrhage; GCS: Glasgow Coma Scale; PHE: perihematomal edema; OR: odds ratio; CI: confidence interval. ^aPer unit change in regressor.