Antioxidant Effect of Melatonin in Preterm Newborns

Table 2

Melatonin, AOPP, NPBI, and F2-Isopr levels in test and control groups at 24 and at 48 hours of life.

	24 hours			48 hours
	Placebo group	MEL group	value	Placebo group	MEL group	value
	[median (25°-75°)]			[median (25°-75°)]
Melatonin (pg/mL)	[10 (1-43)]	[18309 (8886-100831)]	<0.001	[17 (4-121)]	[37349 (10108-274844)]	<0.001
NPBI (micromol/L)	[0.7 (0.2-3.3)]	[4 (1-6)]	0.113	[0.8 (0.1-6)]	[1 (0.6-5)]	0.525
AOPP (micromol/dL)	[36 (28-45)]	[32 (24-42)]	0.297	[53 (33-75)]	[47 (38-60)]	0.715
F2-Isoprostanes (pg/mL)	[80 (31-121)]	[46 (20-93)]	0.168	[80 (62-127)]	[24 (10-68)]	<0.008

Data are expressed as mean SD and median (25-75°C).