I-κB Kinase-ε Deficiency Attenuates the Development of Angiotensin II-Induced Myocardial Hypertrophy in Mice

Figure 6

The lack of IKKε reduced apoptosis in myocardial tissue after Ang II infusion. (a) Representative images and TUNEL assay of WT and IKKε-KO mice after 8 weeks of Ang II infusion ( mice per experimental group, 400x; vs. WT). (b, c) Representative western blots and quantitative analyses of apoptosis-related proteins in the heart tissue of WT and IKKε-KO mice that were infused with Ang II for 8 weeks ( mice per experimental group, vs. saline or WT Ang II).

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