Research Article

[Retracted] S-Nitroso-L-Cysteine Ameliorated Pulmonary Hypertension in the MCT-Induced Rats through Anti-ROS and Anti-Inflammatory Pathways

Figure 3

Effect of CSNO on muscularization and collagen deposition. (a) Immunohistochemical staining of α-SMA in lung tissues. Scale bar: 20 μm. (b) Masson’s trichrome staining of lung tissues. (c) Masson’s trichrome staining of RV tissues. (d) Categorization of pulmonary arteries based on the degree of muscularization, as fully muscularized, partially muscularized, or nonmuscularized vessels. (e, f) Indexes to evaluate collagen deposition in the lung tissues and pulmonary perivascular area. (g) Index to evaluate collagen deposition in RV. (h–j) A comparison of mRNA levels of COL1A1, COL3A1, and Fibronectin by RT-qPCR analysis in lung tissues. . . Data are displayed as . rats. vs. the NC group, # vs. the NT group.