The Secretome Deregulations in a Rat Model of Endotoxemic Shock

Table 3

Proteins with a Log₂foldchange (Log₂FC) greater than 1 are highlighted in bold, and proteins with a Log₂FC less than -1 are not in bold.

UniProt accession number	Protein	Gene name	Protein reference described	Log2FC (range)
Q5GAM5	Angiogenin ribonuclease 2	Ang2	—	1.79 (1.32; 3.47)	4/6
Q6MG90	C4a anaphylatoxin	C4a		-3.22 (-1.42; -6.85)	6/6
D3ZQ25	Fibulin-1	Fbln1		-2.37 (1.24; 5.70)
Q5M890	Apolipoprotein N	Apon	—	-4.55 (-1.46; -5.61)
Q5M8C3	Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4	Serpina4	—	-1.59 (-1.11; -2.75)
Q64240	Protein AMBP	Ambp	[28]	-3.25 (-1.09; -5.11)
B1H260	Coagulation factor XIII B chain	F13b	—	-3.86 (-1.07; -5.12)	5/6
F1LZ11	Ig-like domain-containing protein	N/A	—	-1.72 (-1.00; -3.56)
A0A0G2JXI1	Coagulation factor V	F5	[29]	-2.23 (-1.76; -4.25)	4/6
P08649	Complement C4	C4	[30]	-3.14 (-1.16; -4.59)
P07151	Beta-2-microglobulin	B2m	[31]	-1.51 (-1.32; -2.36)

represent the number of rats in which the protein has been found to be deregulated over the 6 rats. Proteins with an asterisk have already been described in the context of sepsis and septic shock.