Oxidative Medicine and Cellular Longevity

Research Article

Increased Oxidative Stress in Gastric Cancer Patients and Their First-Degree Relatives: A Prospective Study from Northeastern Brazil

Table 4

Comparison of serum GSH concentration, CAT activity, MDA concentration, and SOD activity between controls and familial gastric cancer patients.
UnivariateCGRelatives of GC
GSH337.76 (112.18-561)225.12 (117.47-438.06)0.147
CAT0.97 (0.69-1.42)2.71 (1.53-5.38)<0.001
MDA3.85 (3.33-6.47)5.37 (3.6-10.82)0.051
SOD0.66 (0.58-0.77)1.04 (0.83-1.15)<0.001
MultivariateCGRelatives of GC
GSH313.36 (312.45-373.49)256.29 (255.88-305.12)0.258
CAT1.05 (0.97-1.1)3.81 (3.51-3.93)<0.001
MDA5.15 (4.93-5.79)7.95 (7.78-8.92)0.003
SOD0.67 (0.67-0.68)1.04 (1-1.05)<0.001
Values estimated for generalized linear model gama-log: intercept, sex, smoking, cancer, and age. Data presented as median (25th percentile-75th percentile). CG control group and relatives of gastric cancer.