Increased Oxidative Stress in Gastric Cancer Patients and Their First-Degree Relatives: A Prospective Study from Northeastern Brazil

Table 5

Comparison of serum GSH concentration, CAT activity, MDA concentration, and SOD activity and between gastric cancer patients and familial gastric cancer patients.

Univariate	Relatives of GC	GC
GSH	225.12 (117.47-438.06)	125.72 (46.29-220.41)	0.001
CAT	2.71 (1.53-5.38)	0.95 (0.43-1.33)	<0.001
MDA	5.37 (3.6-10.82)	6.32 (3.94-12.13)	0.627
SOD	1.04 (0.83-1.15)	0.6 (0.48-0.73)	<0.001
Multivariate	Relatives of GC	GC
GSH	262.51 (255.84-275.57)	144.64 (127.23-152.63)	0.018
CAT	3.82 (3.47-4.05)	0.91 (0.78-1.09)	<0.001
MDA	7.58 (7.25-9.12)	9.25 (7.99-10.46)	0.659
SOD	1.04 (1-1.05)	0.6 (0.59-0.61)	<0.001

Values estimated for generalized linear model gama-log: intercept, sex, smoking, cancer, and age. Data presented as median (25th percentile-75th percentile). GC: gastric cancer.