Serum Fetuin-B Levels Are Elevated in Women with Metabolic Syndrome and Associated with Increased Oxidative Stress

Table 1

Main clinical features and serum fetuin-B levels in MetS and control subjects.

Variable	Controls ()	MetS ()
Age (years)^‡			<0.001
BMI (kg/m^2)			<0.001
FAT (%)			<0.001
WHR^‡			<0.001
SBP (mmHg)			<0.001
DBP (mmHg)			<0.001
TC (mmol/L)			<0.001
TG (mmol/L)^†			<0.001
HDL-C (mmol/L)^†			<0.001
LDL-C (mmol/L)			<0.001
FFA (μmol/L)			<0.001
HbA1c (%)^‡			<0.001
FBG (mmol/L)^‡			<0.001
2 h-BG (mmol/L)^†	5.57 (4.85-6.44)	9.46 (7.55-12.02)	<0.001
FIns (mU/L)^†	6.79 (5.70-8.28)	17.94 (11.46-27.51)	<0.001
2 h-Ins (mU/L)^†	41.09 (26.13-60.29)	124.10 (67.76-221.90)	<0.001
HOMA-IR^†	1.43 (1.16-1.78)	5.13 (3.42-7.51)	<0.001
LAP^†	11.50 (5.36-20.71)	65.84 (48.29-89.02)	<0.001
VAI^†	1.23 (0.85-1.74)	3.55 (2.58-4.81)	<0.001
Fetuin-B (mg/L)			<0.001
Fetuin-B (mg/L)^§			<0.001

Values are given as or median (interquartile range). Abbreviations: BMI: body mass index; FAT%: the percentage of fat in vivo; WHR: waist-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FFA: free fatty acid; FBG: fasting blood glucose; 2 h-BG: 2 h blood glucose after glucose overload; FIns: fasting plasma insulin; 2 h-Ins: 2 h plasma insulin after glucose overload; HbA1c: glycosylated hemoglobin; HOMA-IR: homeostasis model assessment of insulin resistance; LAP: lipid accumulation product; VAI: visceral adiposity index. ^†Log transformed before analysis; ^‡nonparametric tests; ^§ error by general linear model with adjustment of age and BMI.