Qiangji Jianli Decoction Alleviates Hydrogen Peroxide-Induced Mitochondrial Dysfunction via Regulating Mitochondrial Dynamics and Biogenesis in L6 Myoblasts

Figure 1

Effects of QJJLD-containing serum on the H₂O₂-induced oxidative stress damage. (a, b) HPLC chromatograms of the standard component mixture and QJJLD. ① Calycosin-7-glucoside, ② liquiritin, ③ ferulic acid, ④ isoferulic acid, ⑤ hesperidin, ⑥ lobetyolin, ⑦ astragaloside IV, ⑧ monoammonium glycyrrhizinate, ⑨ saikosaponin A, ⑩ saikosaponin D, and ⑪ atractylenolide III. (c) Cells were exposed to various concentrations of H₂O₂ for 1 h, and then, cell viability was assessed using the MTT assay (). (d) Attenuation of H₂O₂-induced cytotoxicity by QJJLD-containing serum in L6 myoblasts (). The results are shown as the obtained from five independent experiments. Compared with the normal group, and . Compared with the model group, ^## and ^#.

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