Chinese Herbal Prescription Fu-Zheng-Qu-Xie Prevents Recurrence and Metastasis of Postoperative Early-Stage Lung Adenocarcinoma: A Prospective Cohort Study Followed with Potential Mechanism Exploration

Figure 6

The FZQX prescription suppressed lung cancer progression by inhibiting the IL-1β/NF-κB pathway in vivo. (a) Representative photographs of xenograft tumors in each group. (b) The volume of the xenograft tumors harvested from mice in each group. (c) Western blot detected the expression levels of tumor progression-related proteins and MDSCs related key proteins in the IL-1β/NF-κB signaling pathway. NS: the normal saline group (control); NF-κB inhibitor: mice were injected intraperitoneally with SC75741 (15 mg/kg); NF-κB inhibitor + F: mice were given the FZQX prescription and injected intraperitoneal with SC75741 intraperitoneally.

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