Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy

<div>Oxyberberine inhibited LPS-induced mitophagy in Western blot assay in A549 cells. Representative Western blot images (a) and summarized data (b, c, d) showing the inhibitory effect of oxyberberine on the changes of COX IV, P62, and Mfn2 in A549 cells with or without LPS and oxyberberine treatment. RepresentativeWestern blot images and summarized data showing the Parkin protein level in cytoplasm (e) and mitochondria (f) in A549 cells with or without LPS and oxyberberine treatment. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy 