Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy

<div>Inhibition of mitophagy with Baf prevented the inhibitory effect of oxyberberine on LPS-induced mitophagy in Western blot assay in A549 cells. Representative Western blot images (a) and summarized data showing that Baf prevented the inhibitory effect of oxyberberine on LPS-induced decrease of COX IV (b), P62 (c), and Mfn2 (d). Representative Western blot images and summarized data showing the Parkin protein level in cytoplasm (e) and mitochondria (f) in A549 cells with or without LPS, Baf and oxyberberine treatment. 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Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Oxyberberine Prevented Lipopolysaccharide-Induced Acute Lung Injury through Inhibition of Mitophagy 