The Antioxidant Enzyme PON1: A Potential Prognostic Predictor of Acute Ischemic Stroke

Table 3

Association of serum PON1 quartiles with a 3-month good outcome.

Serum PON1	OR (95% CI), value
	Q1 ()	Q2 ()	Q3 ()	Q4 ()
Model 1	1 (reference)	0.903; (0.612-0.931)	0.674; (0.350-0.926)	0.531; (0.373-0.904)
Model 2	1 (reference)	0.846; (0.358-0.910)	0.639; (0.362-0.876)	0.614; (0.327-0.834)
Model 3	1 (reference)	0.718; (0.303-0.859)	0.627; (0.391-0.814)	0.556; (0.397-0.852)

Model 1 includes age, sex, BMI, and current smoking. Model 2 further includes HP, HLP, DM, CHD, AF, leukocyte, hemoglobin, TC, TG, LDL-C, HDL-C, FBG, and HbA1c. Model 3 further includes NIHSS. PON1: paraoxonase 1; BMI: body mass index; HP: hypertension; HLP: hyperlipidemia; DM: diabetes mellitus; CHD: coronary heart disease; AF: atrial fibrillation; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; FBG: fasting blood glucose; HbA1c: hemoglobin A1c; NIHSS: National Institute of Health Stroke Scale; mRS: modified Rankin Scale.