Research Article
Tea Polyphenol Attenuates Oxidative Stress-Induced Degeneration of Intervertebral Discs by Regulating the Keap1/Nrf2/ARE Pathway
| | Morphology change under optical microscope | Grade |
| | I | Annulus fibrosus (AF) | Normal texture and free of damage and distortion | 1 | | The damaged and distortion area is less than 30% | 2 | | The damaged and distortion area is more than 30% | 3 |
| | II | Boundary between AF and NP | Normal | 1 | | Micro disrupted | 2 | | Medium or severe disrupted | 3 |
| | III | NP cells | Normal cells with large amounts of vacuoles | 1 | | Cells and vacuoles decreased slightly | 2 | | Cells decreased moderately or severely without vacuoles | 3 |
| | IV | NP matrix | Normal gel appearance | 1 | | Slightly congealed | 2 | | Moderate or severe condensation | 3 |
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