Catalpol-Induced AMPK Activation Alleviates Cisplatin-Induced Nephrotoxicity through the Mitochondrial-Dependent Pathway without Compromising Its Anticancer Properties

Figure 6

Molecule docking simulation of compounds with 5UFU. Catalpol (a), phenformin (b), metformin (c), and danthron (d) bind to the active site of 5UFU.

(a) CAT, total score: 6.6864

(b) Phenformin, total score: 6.524

(c) Metoformin, total score: 4.205

(d) Danthron, total score: 5,103