Oxidative Medicine and Cellular Longevity

Research Article

Effect of Vitamin D3 in combination with Omega-3 Polyunsaturated Fatty Acids on NETosis in Type 2 Diabetes Mellitus Patients

Table 1

Hematology and biochemistry parameters in patients who received standard treatment alone and patients who additionally received vitamin D3/omega-3 PUFAs. Displayed are median values with minimum and maximum values in parentheses. ND: no statistically significant difference between groups.
ParametersPatients on standard treatmentPatients on standard treatment+vitamin D3/omega-3 PUFAsSignificant difference
Age (years)69 (58, 80)59 (50, 89)ND
Gender (M/F)3/53/3ND
HbA1c (%)8.8 (7.4, 14.8)9.2 (8.4, 13.1)ND
Baseline blood glucose (mmol/L)9.6 (2.3, 17.5)7.5 (5.0, 16.3)ND
25-Hydroxyvitamin D3 (ng/mL)7.3 (7.0, 17.1)7.8 (5.1, 12.0)ND
ESR (mm/h)49 (8, 59)42 (2, 60)ND
ALT (U/L)17.6 (6.2, 51.8)11.3 (8.0, 27.3)ND
AST (U/L)20.1 (10.2, 26.9)19.5 (10.2, 35.0)ND
Creatinine (μmol/L)84.9 (78.4, 133.3)107.1 (57.1, 179.6)ND
Urea (mmol/L)7.3 (3.7, 10.4)7.3 (3.2, 10.7)ND
Leukocytes (×109/L)9.8 (7.1, 31.4)10.0 (5.6, 17.7)ND