The Activation of ROS/NF-<i>κ</i>B/MMP-9 Pathway Promotes Calcium-Induced Kidney Crystal Deposition

<div>Effects of high concentration of calcium on cell apoptosis and intracellular ROS level in NRK-52E cells. (a) Flow cytometry was used to determine the proportion of apoptotic cells after treatment with high concentration of calcium for 24 hours. (b) The bar graphs showed the proportion of apoptotic cells in each group. (c) Flow cytometry was used to detect the production of ROS in cells treated with high concentration of calcium for 24 hours. The bar graphs showed the relative fluorescence intensity of each group. (d) Ultrastructural changes of cells treated with high concentration of calcium for 24 hours under TEM. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: The Activation of ROS/NF-<i>κ</i>B/MMP-9 Pathway Promotes Calcium-Induced Kidney Crystal Deposition 

Oxidative Medicine and Cellular Longevity

The Activation of ROS/NF-κB/MMP-9 Pathway Promotes Calcium-Induced Kidney Crystal Deposition

Figure 1