Activation of Nrf2 by miR-152 Inhibits Doxorubicin-Induced Cardiotoxicity via Attenuation of Oxidative Stress, Inflammation, and Apoptosis

Figure 3

miR-152 supplementation attenuated myocardial inflammation accumulation in mice with DOX. (a–c) The mRNA levels of inflammatory factors in the hearts (). (d–g) Myocardial inflammatory factors as detected by ELISA (). (h) NF-κB activity in mice (). (i) NF-κB in the nucleus (). Values represent the . versus NS+miR-scramble, ^# versus DOX+miR-scramble.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)