Activation of Nrf2 by miR-152 Inhibits Doxorubicin-Induced Cardiotoxicity via Attenuation of Oxidative Stress, Inflammation, and Apoptosis

Figure 5

The role of miR-152 in cardiomyocytes. (a) miR-152 expression in cardiomyocytes (). (b, c) The mRNA levels of inflammatory factors in cardiomyocytes (). (d) NF-κB activity in cardiomyocytes (). (e, f) ROS and superoxide in cardiomyocytes (). (g) MDA production in cardiomyocytes (). (h) Cell viability in cardiomyocytes (). (i) miR-152 expression in cardiomyocytes (). (j) The mRNA levels of inflammatory factors in cardiomyocytes (). (k, l) ROS and superoxide in cardiomyocytes (). (m) Cell viability in cardiomyocytes (). (n, o) The mRNA levels of inflammatory factors in cardiomyocytes (). (p) NF-κB activity in cardiomyocytes (). Values represent the . versus the matched control.

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