Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells

<div>DAC induces the apoptosis by reducing p-Tyr and BCR-ABL. The 0.5 <i>μ</i>M of DAC and 0.1 <i>μ</i>M of imatinib treatment of K562, K562/R, and K562/TIGAR cells is shown, and the BCR-ABL protein (a) and apoptosis (b) were assessed by FCM. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells 