Downregulation of miR-128 Ameliorates Ang II-Induced Cardiac Remodeling via SIRT1/PIK3R1 Multiple Targets

<div>Summary figure of the information in this study. <svg height="7.35473pt" id="M129" style="vertical-align:-0.3499303pt" version="1.1" viewbox="-0.0498162 -7.0048 7.75925 7.35473" width="7.75925pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M573 255C573 407 448 530 294 530S15 407 15 255S140 -20 294 -20S573 103 573 255ZM520 280H323V484C426 471 508 386 520 280ZM265 280H68C80 386 162 471 265 484V280ZM265 26C162 39 80 124 68 230H265V26ZM520 230C508 124 426 39 323 26V230H520Z"></path></g></svg> activation and <svg height="7.34169pt" id="M130" style="vertical-align:-0.3499303pt" version="1.1" viewbox="-0.0498162 -6.99176 7.75925 7.34169" width="7.75925pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M573 255C573 407 448 530 294 530S15 407 15 255S140 -20 294 -20S573 103 573 255ZM521 255C521 127 419 24 294 24S67 127 67 255S169 486 294 486S521 383 521 255ZM414 230V280H173V230H414Z"></path></g></svg> inhibition.</div>

Oxidative Medicine and Cellular Longevity

fig8

Figure 8

Figure 8: Downregulation of miR-128 Ameliorates Ang II-Induced Cardiac Remodeling via SIRT1/PIK3R1 Multiple Targets 