Green Tea (Camellia sinensis) Extract Increased Topoisomerase IIβ, Improved Antioxidant Defense, and Attenuated Cardiac Remodeling in an Acute Doxorubicin Toxicity Model

Table 4

Cardiac oxidative stress forty-eight hours after doxorubicin injection.

	C ()	GT ()	D ()	DGT ()
LH (nmol/g of tissue)					<0,001	0,002	0,22
CAT (μmol/g of tissue)					0,002	0,30	<0,001
SOD (nmol/g of tissue)					0,01	0,01	<0,001
GPx (nmol/g of tissue)					0,01	0,70	<0,001

Groups: C: control; GT: green tea; D: doxorubicin; DGT: doxorubicin+green tea. LH: lipid hydroperoxide; CAT: catalase; SOD: superoxide dismutase; GPx: glutathione peroxidase. Values are expressed in . value: two-way ANOVA. : value of interaction; : value of green tea; : value of doxorubicin. We observed the interaction between factors in all the variables evidenced by . LH: , . CAT: , . SOD: , , and . GPx: , .