1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation

<div>1-NP-induced nuclear translocation of AIF in RAW264.7 cells. The expression of AIF in mitochondria (a) and nucleus (b) was measured by western blot assay after treated with 1-NP for 24 h. The change in fold of AIF expression between the treated and control groups was calculated. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: 1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation 

Figure 4 | 1-Nitropyrene Induced Reactive Oxygen Species–Mediated Apoptosis in Macrophages through AIF Nuclear Translocation and AMPK/Nrf-2/HO-1 Pathway Activation 